MolNFT v1 · #283996 · protein
AlphaFold monomer V2.0 prediction for orexin receptor type 2 (P58308)
P58308: “AlphaFold monomer V2.0 prediction for orexin receptor type 2 (P58308)”. 6 pockets (best druggability 0.80). MolNFT v1 #283996 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P58308
- Type
- protein
- Length
- 460 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
- Molecule
- Orexin receptor type 2
- UniProt
- P58308
- Pockets
- 6 · best druggability 0.80
Structure
1 distinct chain · 64% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Orexin receptor type 2 | protein | 460 | 64% helix, 3% strand | P58308 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 798 | 0.80 | 0.83 | 64 | empty |
| 2 | 422 | 0.65 | 0.78 | 34 | empty |
| 3 | 254 | 0.54 | 0.76 | 28 | empty |
| 4 | 120 | 0.41 | 0.75 | 17 | empty |
| 5 | 69 | 0.33 | 0.75 | 12 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P58308
- Elsewhere: UniProt P58308 · AlphaFold DB P58308
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