MolNFT v1 · #283982 · protein
AlphaFold monomer V2.0 prediction for orexin receptor type 1 (P58307)
P58307: “AlphaFold monomer V2.0 prediction for orexin receptor type 1 (P58307)”. 6 pockets (best druggability 0.80). MolNFT v1 #283982 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P58307
- Type
- protein
- Length
- 416 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
- Molecule
- Orexin receptor type 1
- UniProt
- P58307
- Pockets
- 6 · best druggability 0.80
Structure
1 distinct chain · 71% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Orexin receptor type 1 | protein | 416 | 71% helix, 3% strand | P58307 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 706 | 0.80 | 0.84 | 57 | empty |
| 2 | 209 | 0.54 | 0.77 | 25 | empty |
| 3 | 83 | 0.51 | 0.83 | 18 | empty |
| 4 | 200 | 0.51 | 0.77 | 26 | empty |
| 5 | 106 | 0.39 | 0.75 | 22 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P58307
- Elsewhere: UniProt P58307 · AlphaFold DB P58307
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