MolNFT v1 · #283747 · protein

AlphaFold monomer V2.0 prediction for otoferlin (Q9ESF1)

Q9ESF1: “AlphaFold monomer V2.0 prediction for otoferlin (Q9ESF1)”. 20 pockets (best druggability 0.81). MolNFT v1 #283747 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9ESF1
Type: protein
Length: 1,997 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
Molecule: Otoferlin
UniProt: Q9ESF1
Pockets: 20 · best druggability 0.81

Structure

1 distinct chain · 18% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Otoferlin	protein	1997	18% helix, 34% strand	Q9ESF1

Pockets

20 pockets found on a 1 Å grid, 16 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	737	0.81	0.84	76	empty
2	844	0.80	0.83	85	empty
3	946	0.77	0.80	95	empty
4	1170	0.74	0.77	77	empty
5	473	0.72	0.82	56	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9ESF1
Elsewhere: UniProt Q9ESF1 · AlphaFold DB Q9ESF1

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