MolNFT v1 · #281766 · protein

AlphaFold monomer V2.0 prediction for melanopsin (Q4R1I4)

Q4R1I4: “AlphaFold monomer V2.0 prediction for melanopsin (Q4R1I4)”. 9 pockets (best druggability 0.84). MolNFT v1 #281766 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q4R1I4
Type: protein
Length: 706 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
Molecule: Melanopsin
UniProt: Q4R1I4
Pockets: 9 · best druggability 0.84

Structure

1 distinct chain · 48% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Melanopsin	protein	706	48% helix, 3% strand	Q4R1I4

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	182	0.84	0.98	31	empty
2	459	0.65	0.77	44	empty
3	289	0.56	0.77	30	empty
4	111	0.53	0.81	22	empty
5	193	0.51	0.76	29	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4R1I4
Elsewhere: UniProt Q4R1I4 · AlphaFold DB Q4R1I4

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