MolNFT v1 · #281363 · protein

AlphaFold monomer V2.0 prediction for oncostatin-M (P13725)

P13725: “AlphaFold monomer V2.0 prediction for oncostatin-M (P13725)”. 2 pockets (best druggability 0.54). MolNFT v1 #281363 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P13725
Type: protein
Length: 252 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x320d59A32cDD20f65Fd6bcCbb9bA5fcfE4Dd1A21
Molecule: Oncostatin-M
UniProt: P13725
Pockets: 2 · best druggability 0.54

Structure

1 distinct chain · 56% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Oncostatin-M	protein	252	56% helix, 0% strand	P13725

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	219	0.54	0.77	28	empty
2	64	0.28	0.73	11	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1EVS · Crystal structure of human oncostatin M · an experimental structure of the same protein · chain A against A, TM-score 0.64
1EVS · Crystal structure of human oncostatin M · an experimental structure of the same protein · chain A against A, TM-score 0.64

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P13725
Elsewhere: UniProt P13725 · AlphaFold DB P13725

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