GL1X · GenesisL1 explorer

MolNFT v1 · #280713 · protein

AlphaFold monomer V2.0 prediction for 8-oxoguanine DNA GLYCOSYLASE/AP lyase (Q97ZK2)

Q97ZK2: “AlphaFold monomer V2.0 prediction for 8-oxoguanine DNA GLYCOSYLASE/AP lyase (Q97ZK2)”. 1 pocket (best druggability 0.53). MolNFT v1 #280713 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q97ZK2
Type
protein
Length
207 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
Molecule
8-oxoguanine DNA GLYCOSYLASE/AP lyase
UniProt
Q97ZK2
Pockets
1 · best druggability 0.53

Structure

1 distinct chain · 71% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A8-oxoguanine DNA GLYCOSYLASE/AP lyaseprotein20771% helix, 0% strandQ97ZK2

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11180.530.8226empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 3FHG · Crystal structure of Sulfolobus solfataricus 8-oxoguanine DNA glycosylase (SsOgg) · an experimental structure of the same protein · chain A against A, TM-score 0.99
  • 3FHG · Crystal structure of sulfolobus solfataricus 8-oxoguanine DNA glycosylase (ssogg) · an experimental structure of the same protein · chain A against A, TM-score 0.99

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