MolNFT v1 · #279001 · protein
AlphaFold monomer V2.0 prediction for 2'-5'-oligoadenylate synthase 2 (P29728)
P29728: “AlphaFold monomer V2.0 prediction for 2'-5'-oligoadenylate synthase 2 (P29728)”. 10 pockets (best druggability 0.72). MolNFT v1 #279001 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P29728
- Type
- protein
- Length
- 719 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc1d1Fc8447De144049a7097d1582A1044C1928dd
- Molecule
- 2'-5'-oligoadenylate synthase 2
- UniProt
- P29728
- Pockets
- 10 · best druggability 0.72
Structure
1 distinct chain · 46% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 2'-5'-oligoadenylate synthase 2 | protein | 719 | 46% helix, 13% strand | P29728 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 382 | 0.72 | 0.83 | 39 | empty |
| 2 | 400 | 0.68 | 0.81 | 47 | empty |
| 3 | 284 | 0.58 | 0.78 | 38 | empty |
| 4 | 185 | 0.57 | 0.80 | 24 | empty |
| 5 | 160 | 0.55 | 0.80 | 26 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29728
- Elsewhere: UniProt P29728 · AlphaFold DB P29728
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