MolNFT v1 · #278978 · protein

AlphaFold monomer V2.0 prediction for omega-amino acid--pyruvate aminotransferase (P28269)

P28269: “AlphaFold monomer V2.0 prediction for omega-amino acid--pyruvate aminotransferase (P28269)”. 2 pockets (best druggability 0.71). MolNFT v1 #278978 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P28269
Type: protein
Length: 449 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xcf977Dc0CD62329D4750FCa1152B6633Bf4D477b
Molecule: Omega-amino acid--pyruvate aminotransferase
UniProt: P28269
Pockets: 2 · best druggability 0.71

Structure

1 distinct chain · 40% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Omega-amino acid--pyruvate aminotransferase	protein	449	40% helix, 17% strand	P28269

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	777	0.71	0.77	73	empty
2	443	0.68	0.79	37	empty

Compared structures

3A8U · Crystal structure of omega-amino ACID:PYRUVATE aminotransferase · an experimental structure of the same protein · chain A against X, TM-score 0.98
3A8U · Crystal Structure of omega-Amino Acid:Pyruvate Aminotransferase · an experimental structure of the same protein · chain A against X, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P28269
Elsewhere: UniProt P28269 · AlphaFold DB P28269

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