GL1X · GenesisL1 explorer

MolNFT v1 · #278298 · protein

AlphaFold monomer V2.0 prediction for neurexophilin-1 (Q63366)

Q63366: “AlphaFold monomer V2.0 prediction for neurexophilin-1 (Q63366)”. 2 pockets (best druggability 0.67). MolNFT v1 #278298 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q63366
Type
protein
Length
271 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x00C4b10Cc8bd9708A9f628aB5dfeBF165b7137C2
Molecule
Neurexophilin-1
UniProt
Q63366
Pockets
2 · best druggability 0.67

Structure

1 distinct chain · 7% helix, 37% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANeurexophilin-1protein2717% helix, 37% strandQ63366

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12260.670.8438empty
21040.360.7428empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

  • 6PNQ · Crystal structure of the SS2A splice insert-containing neurexin-1 LNS2 domain in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.48
  • 6PNQ · Crystal structure of the SS2A splice insert-containing neurexin-1 LNS2 domain in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.48
  • 6PNP · Crystal structure of the splice insert-free neurexin-1 LNS2 domain in complex with… · an experimental structure of the same protein · chain A against B, TM-score 0.48
  • 6PNP · Crystal structure of the splice insert-free neurexin-1 LNS2 domain in complex with… · an experimental structure of the same protein · chain A against B, TM-score 0.48

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