GL1X · GenesisL1 explorer

MolNFT v1 · #278260 · protein

AlphaFold monomer V2.0 prediction for nuclear RNA export factor 1 (Q9UBU9)

Q9UBU9: “AlphaFold monomer V2.0 prediction for nuclear RNA export factor 1 (Q9UBU9)”. 3 pockets (best druggability 0.30). MolNFT v1 #278260 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9UBU9
Type
protein
Length
619 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5998bFB2F22991b222F61c8c1535024ca911B6b8
Molecule
Nuclear RNA export factor 1
UniProt
Q9UBU9
Pockets
3 · best druggability 0.30

Structure

1 distinct chain · 30% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANuclear RNA export factor 1protein61930% helix, 17% strandQ9UBU9

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1580.300.7514empty
2580.300.7512empty
3540.290.7512empty

Compared structures

  • 4WYK · Structure of the lrr and NTF2-like domains of NXF1 complexed with NXT1 · an experimental structure of the same protein · chain A against C, TM-score 0.54
  • 4WYK · Structure of the LRR and NTF2-like domains of NXF1 complexed with NXT1 · an experimental structure of the same protein · chain A against C, TM-score 0.54
  • 3RW6 · Structure of nuclear RNA export factor TAP bound to CTE RNA · an experimental structure of the same protein · chain A against B, TM-score 0.38
  • 3RW6 · Structure of nuclear RNA export factor tap bound to cte RNA · an experimental structure of the same protein · chain A against B, TM-score 0.38
  • 6E5U · Crystal structure of the mRNA export receptor NXF1/NXT1 in complex with influenza virus… · an experimental structure of the same protein · chain A against A, TM-score 0.35
  • 1JN5 · Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain… · an experimental structure of the same protein · chain A against B, TM-score 0.28
  • 1JN5 · Structural basis for the recognition of a nucleoporin fg- repeat by the NTF2-like domain… · an experimental structure of the same protein · chain A against B, TM-score 0.28
  • 1JKG · Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain… · an experimental structure of the same protein · chain A against B, TM-score 0.28

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