MolNFT v1 · #277418 · protein
AlphaFold monomer V2.0 prediction for nucleoporin NUP84 (P52891)
P52891: “AlphaFold monomer V2.0 prediction for nucleoporin NUP84 (P52891)”. 8 pockets (best druggability 0.69). MolNFT v1 #277418 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P52891
- Type
- protein
- Length
- 726 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB8A77C885f877Ea23Ed1B779cdfDE4aA48d69ed6
- Molecule
- Nucleoporin NUP84
- UniProt
- P52891
- Pockets
- 8 · best druggability 0.69
Structure
1 distinct chain · 69% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoporin NUP84 | protein | 726 | 69% helix, 1% strand | P52891 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 437 | 0.69 | 0.80 | 44 | empty |
| 2 | 63 | 0.53 | 0.87 | 16 | empty |
| 3 | 127 | 0.52 | 0.81 | 29 | empty |
| 4 | 134 | 0.52 | 0.80 | 20 | empty |
| 5 | 115 | 0.45 | 0.78 | 23 | empty |
Compared structures
- 6X02 · NUP84-NUP133 (AA521-1157) from S. cerevisiae bound by vhh-SAN8 · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 6X03 · NUP84-NUP133 (AA521-1157) from S. cerevisiae bound by vhh-SAN8 and vhh-SAN9 · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 7N84 · Double nuclear outer ring from the isolated yeast npc · an experimental structure of the same protein · chain A against f, TM-score 0.75
- 4XMN · Structure of the yeast coat nucleoporin complex, space group P212121 · an experimental structure of the same protein · chain A against F, TM-score 0.57
- 4XMN · Structure of the yeast coat nucleoporin complex, space group P212121 · an experimental structure of the same protein · chain A against F, TM-score 0.57
- 4XMM · Structure of the yeast coat nucleoporin complex, space group C2 · an experimental structure of the same protein · chain A against F, TM-score 0.57
- 4XMM · Structure of the yeast coat nucleoporin complex, space group C2 · an experimental structure of the same protein · chain A against F, TM-score 0.57
- 3IKO · Crystal structure of the heterotrimeric Sec13-Nup145C-Nup84 nucleoporin complex · an experimental structure of the same protein · chain A against C, TM-score 0.57
- 3IKO · Crystal structure of the heterotrimeric SEC13-NUP145C-NUP84 nucleoporin complex · an experimental structure of the same protein · chain A against C, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P52891
- Elsewhere: UniProt P52891 · AlphaFold DB P52891
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