MolNFT v1 · #273928 · protein

AlphaFold monomer V2.0 prediction for mitochondrial nuclease (P08466)

P08466: “AlphaFold monomer V2.0 prediction for mitochondrial nuclease (P08466)”. 3 pockets (best druggability 0.56). MolNFT v1 #273928 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P08466
Type: protein
Length: 329 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xf1FcCd396b340C3792db5B4D2953501B9f0EE59d
Molecule: Mitochondrial nuclease
UniProt: P08466
Pockets: 3 · best druggability 0.56

Structure

1 distinct chain · 22% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Mitochondrial nuclease	protein	329	22% helix, 22% strand	P08466

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	335	0.56	0.75	34	empty
2	164	0.43	0.74	26	empty
3	50	0.28	0.75	12	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08466
Elsewhere: UniProt P08466 · AlphaFold DB P08466

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