MolNFT v1 · #271823 · protein
AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 1 (P03887)
P03887: “AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 1 (P03887)”. 3 pockets (best druggability 0.79). MolNFT v1 #271823 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P03887
- Type
- protein
- Length
- 318 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x01aC486776AfBeE367A940B4DEb7E3121eE9a882
- Molecule
- NADH-ubiquinone oxidoreductase chain 1
- UniProt
- P03887
- Pockets
- 3 · best druggability 0.79
Structure
1 distinct chain · 69% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-ubiquinone oxidoreductase chain 1 | protein | 318 | 69% helix, 0% strand | P03887 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 121 | 0.79 | 0.97 | 27 | empty |
| 2 | 216 | 0.55 | 0.78 | 30 | empty |
| 3 | 192 | 0.50 | 0.76 | 27 | empty |
Compared structures
- 7QSL · Bovine complex I in lipid nanodisc, active-apo · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 7QSL · Bovine complex I in lipid nanodisc, Active-apo · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 7R41 · Bovine complex I in the presence of IM1761092, active class i (Composite map) · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 7R42 · Bovine complex I in the presence of IM1761092, active class ii (Composite map) · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 7R43 · Bovine complex I in the presence of IM1761092, active class iii (Composite map) · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 7QSD · Bovine complex I in the active state at 3.1 a · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 7QSD · Bovine complex I in the active state at 3.1 A · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 7R44 · Bovine complex I in the presence of IM1761092, active class iv (Composite map) · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 7QSK · Bovine complex I in lipid nanodisc, Active-Q10 · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 7QSK · Bovine complex I in lipid nanodisc, active-Q10 · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 8Q45 · Inward-facing, closed proteoliposome complex I at 2.7 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against H, TM-score 1.00
- 8Q0A · Inward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. · an experimental structure of the same protein · chain A against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03887
- Elsewhere: UniProt P03887 · AlphaFold DB P03887
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.