MolNFT v1 · #271681 · protein
AlphaFold monomer V2.0 prediction for nucleoporin NUP186 (P78847)
P78847: “AlphaFold monomer V2.0 prediction for nucleoporin NUP186 (P78847)”. 20 pockets (best druggability 0.75). MolNFT v1 #271681 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P78847
- Type
- protein
- Length
- 1,647 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x22c3Ca87f200b90eA736Db68c0123ECEc125b25E
- Molecule
- Nucleoporin NUP186
- UniProt
- P78847
- Pockets
- 20 · best druggability 0.75
Structure
1 distinct chain · 69% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoporin NUP186 | protein | 1647 | 69% helix, 2% strand | P78847 |
Pockets
20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 123 | 0.75 | 0.94 | 27 | empty |
| 2 | 1079 | 0.71 | 0.75 | 108 | empty |
| 3 | 456 | 0.69 | 0.80 | 34 | empty |
| 4 | 323 | 0.68 | 0.82 | 48 | empty |
| 5 | 695 | 0.68 | 0.76 | 74 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P78847
- Elsewhere: UniProt P78847 · AlphaFold DB P78847
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