MolNFT v1 · #271638 · protein

AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP107 (P57740)

P57740: “AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP107 (P57740)”. 12 pockets (best druggability 0.77). MolNFT v1 #271638 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P57740
Type: protein
Length: 925 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xb3c0C983Fc44934AC589D7131C08a72544EBB92E
Molecule: Nuclear pore complex protein NUP107
UniProt: P57740
Pockets: 12 · best druggability 0.77

Structure

1 distinct chain · 61% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear pore complex protein NUP107	protein	925	61% helix, 0% strand	P57740

Pockets

12 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	769	0.77	0.81	64	empty
2	284	0.59	0.78	27	empty
3	257	0.57	0.78	40	empty
4	178	0.55	0.80	26	empty
5	208	0.55	0.79	29	empty

Compared structures

7R5K · Human nuclear pore complex (constricted) · an experimental structure of the same protein · chain A against L3, TM-score 0.83
7R5J · Human nuclear pore complex (dilated) · an experimental structure of the same protein · chain A against L0, TM-score 0.82
7PEQ · Model of the outer rings of the human nuclear pore complex · an experimental structure of the same protein · chain A against BD, TM-score 0.67

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P57740
Elsewhere: UniProt P57740 · AlphaFold DB P57740

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