MolNFT v1 · #271613 · protein
AlphaFold monomer V2.0 prediction for nt-3 growth factor receptor (P24786)
P24786: “AlphaFold monomer V2.0 prediction for nt-3 growth factor receptor (P24786)”. 7 pockets (best druggability 0.75). MolNFT v1 #271613 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P24786
- Type
- protein
- Length
- 825 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- Nt-3 growth factor receptor
- UniProt
- P24786
- Pockets
- 7 · best druggability 0.75
Structure
1 distinct chain · 23% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nt-3 growth factor receptor | protein | 825 | 23% helix, 26% strand | P24786 |
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1002 | 0.75 | 0.78 | 68 | empty |
| 2 | 584 | 0.72 | 0.80 | 39 | empty |
| 3 | 50 | 0.68 | 0.96 | 17 | empty |
| 4 | 371 | 0.65 | 0.79 | 52 | empty |
| 5 | 258 | 0.52 | 0.75 | 22 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24786
- Elsewhere: UniProt P24786 · AlphaFold DB P24786
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