MolNFT v1 · #271612 · protein
AlphaFold monomer V2.0 prediction for nt-3 growth factor receptor (Q5IS37)
Q5IS37: “AlphaFold monomer V2.0 prediction for nt-3 growth factor receptor (Q5IS37)”. 7 pockets (best druggability 0.71). MolNFT v1 #271612 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5IS37
- Type
- protein
- Length
- 825 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
- Molecule
- Nt-3 growth factor receptor
- UniProt
- Q5IS37
- Pockets
- 7 · best druggability 0.71
Structure
1 distinct chain · 23% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nt-3 growth factor receptor | protein | 825 | 23% helix, 25% strand | Q5IS37 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.71 | 0.96 | 17 | empty |
| 2 | 457 | 0.71 | 0.81 | 51 | empty |
| 3 | 691 | 0.69 | 0.76 | 71 | empty |
| 4 | 298 | 0.54 | 0.75 | 31 | empty |
| 5 | 189 | 0.46 | 0.74 | 33 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5IS37
- Elsewhere: UniProt Q5IS37 · AlphaFold DB Q5IS37
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