MolNFT v1 · #271603 · protein
AlphaFold monomer V2.0 prediction for high affinity nerve growth factor receptor (P35739)
P35739: “AlphaFold monomer V2.0 prediction for high affinity nerve growth factor receptor (P35739)”. 9 pockets (best druggability 0.73). MolNFT v1 #271603 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P35739
- Type
- protein
- Length
- 799 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x45a468Feb33D79C55c3fD400Cd3123718670320C
- Molecule
- High affinity nerve growth factor receptor
- UniProt
- P35739
- Pockets
- 9 · best druggability 0.73
Structure
1 distinct chain · 22% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | High affinity nerve growth factor receptor | protein | 799 | 22% helix, 25% strand | P35739 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 263 | 0.73 | 0.87 | 31 | empty |
| 2 | 651 | 0.73 | 0.80 | 61 | empty |
| 3 | 336 | 0.73 | 0.85 | 45 | empty |
| 4 | 399 | 0.63 | 0.78 | 48 | empty |
| 5 | 225 | 0.53 | 0.77 | 32 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35739
- Elsewhere: UniProt P35739 · AlphaFold DB P35739
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