MolNFT v1 · #271600 · protein
AlphaFold monomer V2.0 prediction for high affinity nerve growth factor receptor (Q91009)
Q91009: “AlphaFold monomer V2.0 prediction for high affinity nerve growth factor receptor (Q91009)”. 9 pockets (best druggability 0.77). MolNFT v1 #271600 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q91009
- Type
- protein
- Length
- 778 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9073C46348542FfE4327c3F363F9B51B22058e75
- Molecule
- High affinity nerve growth factor receptor
- UniProt
- Q91009
- Pockets
- 9 · best druggability 0.77
Structure
1 distinct chain · 25% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | High affinity nerve growth factor receptor | protein | 778 | 25% helix, 27% strand | Q91009 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 687 | 0.77 | 0.82 | 57 | empty |
| 2 | 332 | 0.61 | 0.78 | 31 | empty |
| 3 | 111 | 0.57 | 0.84 | 20 | empty |
| 4 | 185 | 0.47 | 0.75 | 23 | empty |
| 5 | 145 | 0.45 | 0.76 | 26 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q91009
- Elsewhere: UniProt Q91009 · AlphaFold DB Q91009
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