MolNFT v1 · #270721 · protein
AlphaFold monomer V2.0 prediction for 25S rRNA (cytosine-C(5))-methyltransferase NSUN5 (Q8GYE8)
Q8GYE8: “AlphaFold monomer V2.0 prediction for 25S rRNA (cytosine-C(5))-methyltransferase NSUN5 (Q8GYE8)”. 4 pockets (best druggability 0.76). MolNFT v1 #270721 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8GYE8
- Type
- protein
- Length
- 567 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x404dD93cd2E0F7C9B647A7c82A4C1aCbcc756C0A
- Molecule
- 25S rRNA (cytosine-C(5))-methyltransferase NSUN5
- UniProt
- Q8GYE8
- Pockets
- 4 · best druggability 0.76
Structure
1 distinct chain · 36% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 25S rRNA (cytosine-C(5))-methyltransferase NSUN5 | protein | 567 | 36% helix, 10% strand | Q8GYE8 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1145 | 0.76 | 0.79 | 93 | empty |
| 2 | 254 | 0.68 | 0.84 | 30 | empty |
| 3 | 576 | 0.65 | 0.76 | 50 | empty |
| 4 | 59 | 0.29 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8GYE8
- Elsewhere: UniProt Q8GYE8 · AlphaFold DB Q8GYE8
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