MolNFT v1 · #270710 · protein
AlphaFold monomer V2.0 prediction for RNA cytosine-C(5)-methyltransferase NSUN2 (Q28E61)
Q28E61: “AlphaFold monomer V2.0 prediction for RNA cytosine-C(5)-methyltransferase NSUN2 (Q28E61)”. 9 pockets (best druggability 0.77). MolNFT v1 #270710 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q28E61
- Type
- protein
- Length
- 798 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
- Molecule
- RNA cytosine-C(5)-methyltransferase NSUN2
- UniProt
- Q28E61
- Pockets
- 9 · best druggability 0.77
Structure
1 distinct chain · 30% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA cytosine-C(5)-methyltransferase NSUN2 | protein | 798 | 30% helix, 16% strand | Q28E61 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1151 | 0.77 | 0.79 | 97 | empty |
| 2 | 1071 | 0.74 | 0.77 | 83 | empty |
| 3 | 357 | 0.57 | 0.75 | 46 | empty |
| 4 | 134 | 0.53 | 0.81 | 22 | empty |
| 5 | 230 | 0.53 | 0.76 | 35 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q28E61
- Elsewhere: UniProt Q28E61 · AlphaFold DB Q28E61
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