MolNFT v1 · #270709 · protein
AlphaFold monomer V2.0 prediction for RNA cytosine-C(5)-methyltransferase NSUN2 (Q4V7N2)
Q4V7N2: “AlphaFold monomer V2.0 prediction for RNA cytosine-C(5)-methyltransferase NSUN2 (Q4V7N2)”. 6 pockets (best druggability 0.78). MolNFT v1 #270709 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q4V7N2
- Type
- protein
- Length
- 698 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x51854365c26712e025414B337aDf0f8c25Bc18a0
- Molecule
- RNA cytosine-C(5)-methyltransferase NSUN2
- UniProt
- Q4V7N2
- Pockets
- 6 · best druggability 0.78
Structure
1 distinct chain · 37% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA cytosine-C(5)-methyltransferase NSUN2 | protein | 698 | 37% helix, 18% strand | Q4V7N2 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 726 | 0.78 | 0.82 | 75 | empty |
| 2 | 759 | 0.67 | 0.75 | 80 | empty |
| 3 | 397 | 0.60 | 0.76 | 61 | empty |
| 4 | 100 | 0.50 | 0.81 | 22 | empty |
| 5 | 58 | 0.36 | 0.78 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4V7N2
- Elsewhere: UniProt Q4V7N2 · AlphaFold DB Q4V7N2
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