MolNFT v1 · #270266 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB1 (P18616)
P18616: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB1 (P18616)”. 20 pockets (best druggability 0.80). MolNFT v1 #270266 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P18616
- Type
- protein
- Length
- 1,839 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
- Molecule
- DNA-directed RNA polymerase II subunit RPB1
- UniProt
- P18616
- Pockets
- 20 · best druggability 0.80
Structure
1 distinct chain · 33% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase II subunit RPB1 | protein | 1839 | 33% helix, 13% strand | P18616 |
Pockets
20 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 713 | 0.80 | 0.84 | 72 | empty |
| 2 | 531 | 0.78 | 0.84 | 71 | empty |
| 3 | 1046 | 0.74 | 0.77 | 89 | empty |
| 4 | 487 | 0.71 | 0.81 | 58 | empty |
| 5 | 200 | 0.71 | 0.88 | 28 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18616
- Elsewhere: UniProt P18616 · AlphaFold DB P18616
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