MolNFT v1 · #270258 · protein
AlphaFold monomer V2.0 prediction for neuropilin-2 (O35375)
O35375: “AlphaFold monomer V2.0 prediction for neuropilin-2 (O35375)”. 9 pockets (best druggability 0.74). MolNFT v1 #270258 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O35375
- Type
- protein
- Length
- 931 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
- Molecule
- Neuropilin-2
- UniProt
- O35375
- Pockets
- 9 · best druggability 0.74
Structure
1 distinct chain · 9% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuropilin-2 | protein | 931 | 9% helix, 38% strand | O35375 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 627 | 0.74 | 0.81 | 64 | empty |
| 2 | 736 | 0.72 | 0.78 | 67 | empty |
| 3 | 459 | 0.63 | 0.77 | 56 | empty |
| 4 | 145 | 0.55 | 0.82 | 25 | empty |
| 5 | 125 | 0.50 | 0.79 | 27 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O35375
- Elsewhere: UniProt O35375 · AlphaFold DB O35375
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