MolNFT v1 · #270162 · protein
AlphaFold monomer V2.0 prediction for pro-neuregulin-2, membrane- bound isoform (P56974)
P56974 · Pro-neuregulin-2, membrane-bound isoform: “AlphaFold monomer V2.0 prediction for pro-neuregulin-2, membrane- bound isoform (P56974)”. 2 pockets (best druggability 0.54). MolNFT v1 #270162 on GenesisL1: 3D structure, binding sites…
- Accession
- P56974
- Type
- protein
- Length
- 756 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x95359253bA527AB3762b6AD81b50414549F65387
- Molecule
- Pro-neuregulin-2, membrane-bound isoform
- UniProt
- P56974
- Pockets
- 2 · best druggability 0.54
Structure
1 distinct chain · 14% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pro-neuregulin-2, membrane-bound isoform | protein | 756 | 14% helix, 15% strand | P56974 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 265 | 0.54 | 0.76 | 39 | empty |
| 2 | 67 | 0.29 | 0.73 | 14 | empty |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P56974
- Elsewhere: UniProt P56974 · AlphaFold DB P56974
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