MolNFT v1 · #269122 · protein
AlphaFold monomer V2.0 prediction for natural resistance-associated macrophage protein 1 (O77741)
O77741: “AlphaFold monomer V2.0 prediction for natural resistance-associated macrophage protein 1 (O77741)”. 4 pockets (best druggability 0.63). MolNFT v1 #269122 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O77741
- Type
- protein
- Length
- 538 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
- Molecule
- Natural resistance-associated macrophage protein 1
- UniProt
- O77741
- Pockets
- 4 · best druggability 0.63
Structure
1 distinct chain · 74% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Natural resistance-associated macrophage protein 1 | protein | 538 | 74% helix, 1% strand | O77741 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 397 | 0.63 | 0.77 | 49 | empty |
| 2 | 253 | 0.49 | 0.74 | 39 | empty |
| 3 | 118 | 0.45 | 0.77 | 19 | empty |
| 4 | 65 | 0.34 | 0.77 | 22 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O77741
- Elsewhere: UniProt O77741 · AlphaFold DB O77741
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