MolNFT v1 · #269006 · protein

AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 0 group B member 2 (Q62227)

Q62227: “AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 0 group B member 2 (Q62227)”. 2 pockets (best druggability 0.45). MolNFT v1 #269006 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q62227
Type: protein
Length: 260 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x89365364536602e20ca45Af31c26b1889b622007
Molecule: Nuclear receptor subfamily 0 group B member 2
UniProt: Q62227
Pockets: 2 · best druggability 0.45

Structure

1 distinct chain · 61% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear receptor subfamily 0 group B member 2	protein	260	61% helix, 3% strand	Q62227

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	175	0.45	0.75	23	empty
2	50	0.26	0.73	11	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

4NUF · Crystal Structure of SHP/EID1 · an experimental structure of the same protein · chain A against A, TM-score 0.71
4NUF · Crystal structure of SHP/EID1 · an experimental structure of the same protein · chain A against A, TM-score 0.71
1YMT · Mouse SF-1 LBD · an experimental structure of the same protein · chain A against B, TM-score 0.04
1YMT · Mouse sf-1 lbd · an experimental structure of the same protein · chain A against B, TM-score 0.04

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q62227
Elsewhere: UniProt Q62227 · AlphaFold DB Q62227

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