MolNFT v1 · #267921 · protein
AlphaFold monomer V2.0 prediction for npc intracellular cholesterol transporter 1 homolog 1B (Q9VRC9)
Q9VRC9: “AlphaFold monomer V2.0 prediction for npc intracellular cholesterol transporter 1 homolog 1B (Q9VRC9)”. 13 pockets (best druggability 0.89). MolNFT v1 #267921 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9VRC9
- Type
- protein
- Length
- 1,254 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8F9c7747101075C570E34CAd4Ed2A4C01e9b2C28
- Molecule
- Npc intracellular cholesterol transporter 1 homolog 1B
- UniProt
- Q9VRC9
- Pockets
- 13 · best druggability 0.89
Structure
1 distinct chain · 53% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Npc intracellular cholesterol transporter 1 homolog 1B | protein | 1254 | 53% helix, 11% strand | Q9VRC9 |
Pockets
13 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 945 | 0.89 | 0.91 | 115 | empty |
| 2 | 346 | 0.82 | 0.91 | 34 | empty |
| 3 | 995 | 0.77 | 0.79 | 88 | empty |
| 4 | 725 | 0.73 | 0.79 | 66 | empty |
| 5 | 399 | 0.70 | 0.82 | 53 | empty |
Modifications
Observed in the structure: 14 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9VRC9
- Elsewhere: UniProt Q9VRC9 · AlphaFold DB Q9VRC9
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