MolNFT v1 · #267827 · protein

AlphaFold monomer V2.0 prediction for NADPH oxidase 1 (Q8CIZ9)

Q8CIZ9: “AlphaFold monomer V2.0 prediction for NADPH oxidase 1 (Q8CIZ9)”. 8 pockets (best druggability 0.84). MolNFT v1 #267827 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8CIZ9
Type: protein
Length: 591 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xe9f3e03f1c0D674c8ca581614bB1f27977239e4c
Molecule: NADPH oxidase 1
UniProt: Q8CIZ9
Pockets: 8 · best druggability 0.84

Structure

1 distinct chain · 53% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NADPH oxidase 1	protein	591	53% helix, 14% strand	Q8CIZ9

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	888	0.84	0.85	81	empty
2	365	0.76	0.86	44	empty
3	180	0.56	0.80	24	empty
4	99	0.52	0.82	21	empty
5	95	0.41	0.78	18	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8CIZ9
Elsewhere: UniProt Q8CIZ9 · AlphaFold DB Q8CIZ9

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