MolNFT v1 · #267721 · protein
AlphaFold monomer V2.0 prediction for nitric oxide synthase (Q8T8C0)
Q8T8C0: “AlphaFold monomer V2.0 prediction for nitric oxide synthase (Q8T8C0)”. 16 pockets (best druggability 0.80). MolNFT v1 #267721 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8T8C0
- Type
- protein
- Length
- 1,209 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
- Molecule
- Nitric oxide synthase
- UniProt
- Q8T8C0
- Pockets
- 16 · best druggability 0.80
Structure
1 distinct chain · 40% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nitric oxide synthase | protein | 1209 | 40% helix, 17% strand | Q8T8C0 |
Pockets
16 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 678 | 0.80 | 0.85 | 81 | empty |
| 2 | 306 | 0.75 | 0.87 | 48 | empty |
| 3 | 227 | 0.72 | 0.88 | 38 | empty |
| 4 | 495 | 0.70 | 0.80 | 56 | empty |
| 5 | 159 | 0.68 | 0.88 | 24 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8T8C0
- Elsewhere: UniProt Q8T8C0 · AlphaFold DB Q8T8C0
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