GL1X · GenesisL1 explorer

MolNFT v1 · #267313 · protein

AlphaFold monomer V2.0 prediction for nucleolar protein 58 (Q9Y2X3)

Q9Y2X3: “AlphaFold monomer V2.0 prediction for nucleolar protein 58 (Q9Y2X3)”. 2 pockets (best druggability 0.38). MolNFT v1 #267313 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9Y2X3
Type
protein
Length
529 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xCA1bE9A42a4fcF0Fc5B42D27747D04B73Cbb2797
Molecule
Nucleolar protein 58
UniProt
Q9Y2X3
Pockets
2 · best druggability 0.38

Structure

1 distinct chain · 55% helix, 5% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANucleolar protein 58protein52955% helix, 5% strandQ9Y2X3

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1940.380.7620empty
2620.300.7415empty

Compared structures

  • 7MQA · Cryo-EM structure of the human SSU processome, state post-A1 · an experimental structure of the same protein · chain A against SB, TM-score 0.75
  • 7MQ9 · Cryo-EM structure of the human SSU processome, state pre-A1* · an experimental structure of the same protein · chain A against SB, TM-score 0.73
  • 7MQ8 · Cryo-EM structure of the human SSU processome, state pre-A1 · an experimental structure of the same protein · chain A against SB, TM-score 0.72

Analyse

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