GL1X · GenesisL1 explorer

MolNFT v1 · #266747 · protein

AlphaFold monomer V2.0 prediction for nucleolar complex protein 4 (Q06512)

Q06512: “AlphaFold monomer V2.0 prediction for nucleolar complex protein 4 (Q06512)”. 2 pockets (best druggability 0.38). MolNFT v1 #266747 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q06512
Type
protein
Length
552 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xb92D3b0E198eC4a6c8dCd4D0aFDD2FC07B271c2C
Molecule
Nucleolar complex protein 4
UniProt
Q06512
Pockets
2 · best druggability 0.38

Structure

1 distinct chain · 62% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANucleolar complex protein 4protein55262% helix, 1% strandQ06512

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1610.380.7914empty
2790.330.7419empty

Compared structures

  • 7D63 · Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) · an experimental structure of the same protein · chain A against RO, TM-score 0.88
  • 6LQU · Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) · an experimental structure of the same protein · chain A against RO, TM-score 0.88
  • 6LQP · Cryo-EM structure of 90S small subunit preribosomes in transition states (State A) · an experimental structure of the same protein · chain A against RO, TM-score 0.88
  • 6LQQ · Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) · an experimental structure of the same protein · chain A against RO, TM-score 0.88
  • 6LQR · Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) · an experimental structure of the same protein · chain A against RO, TM-score 0.88
  • 6LQV · Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) · an experimental structure of the same protein · chain A against RO, TM-score 0.88
  • 7D5S · Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) · an experimental structure of the same protein · chain A against RO, TM-score 0.88
  • 6KE6 · 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome · an experimental structure of the same protein · chain A against RO, TM-score 0.88
  • 5WLC · The complete structure of the small subunit processome · an experimental structure of the same protein · chain A against SU, TM-score 0.88
  • 7D4I · Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA… · an experimental structure of the same protein · chain A against RO, TM-score 0.87
  • 6LQS · Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) · an experimental structure of the same protein · chain A against RO, TM-score 0.85
  • 6ZQF · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-B… · an experimental structure of the same protein · chain A against US, TM-score 0.85

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