MolNFT v1 · #266365 · protein
AlphaFold monomer V2.0 prediction for 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase (P42882)
P42882: “AlphaFold monomer V2.0 prediction for 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase (P42882)”. 4 pockets (best druggability 0.83). MolNFT v1 #266365 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P42882
- Type
- protein
- Length
- 342 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
- Molecule
- 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase
- UniProt
- P42882
- Pockets
- 4 · best druggability 0.83
Structure
1 distinct chain · 48% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase | protein | 342 | 48% helix, 16% strand | P42882 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 203 | 0.83 | 0.96 | 26 | empty |
| 2 | 269 | 0.77 | 0.90 | 32 | empty |
| 3 | 207 | 0.52 | 0.77 | 29 | empty |
| 4 | 150 | 0.45 | 0.76 | 27 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42882
- Elsewhere: UniProt P42882 · AlphaFold DB P42882
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