MolNFT v1 · #266250 · protein
AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 3A (Q8TCU5)
Q8TCU5: “AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 3A (Q8TCU5)”. 12 pockets (best druggability 0.60). MolNFT v1 #266250 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8TCU5
- Type
- protein
- Length
- 1,115 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
- Molecule
- Glutamate receptor ionotropic, NMDA 3A
- UniProt
- Q8TCU5
- Pockets
- 12 · best druggability 0.60
Structure
1 distinct chain · 40% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutamate receptor ionotropic, NMDA 3A | protein | 1115 | 40% helix, 14% strand | Q8TCU5 |
Pockets
12 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 311 | 0.60 | 0.78 | 42 | empty |
| 2 | 207 | 0.56 | 0.79 | 29 | empty |
| 3 | 156 | 0.51 | 0.79 | 20 | empty |
| 4 | 156 | 0.45 | 0.76 | 32 | empty |
| 5 | 105 | 0.41 | 0.76 | 14 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 8USX · Glycine-bound GluN1a-3A NMDA receptor · an experimental structure of the same protein · chain A against D, TM-score 0.41
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TCU5
- Elsewhere: UniProt Q8TCU5 · AlphaFold DB Q8TCU5
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