MolNFT v1 · #266075 · protein

AlphaFold monomer V2.0 prediction for sodium-dependent lysophosphatidylcholine symporter 1 (Q8NA29)

Q8NA29: “AlphaFold monomer V2.0 prediction for sodium-dependent lysophosphatidylcholine symporter 1 (Q8NA29)”. 5 pockets (best druggability 0.85). MolNFT v1 #266075 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8NA29
Type: protein
Length: 543 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x82785E70A1E767e03Fb666d37ebBB9690126A077
Molecule: Sodium-dependent lysophosphatidylcholine symporter 1
UniProt: Q8NA29
Pockets: 5 · best druggability 0.85

Structure

1 distinct chain · 71% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sodium-dependent lysophosphatidylcholine symporter 1	protein	543	71% helix, 1% strand	Q8NA29

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1154	0.85	0.85	101	empty
2	82	0.45	0.81	23	empty
3	126	0.40	0.75	16	empty
4	52	0.31	0.77	11	empty
5	55	0.28	0.75	14	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

7OIX · Structure of thermostable human MFSD2A in complex with thermostable human SYNC2 · an experimental structure of the same protein · chain A against B, TM-score 0.80
7OIX · Structure of thermostable human MFSD2A in complex with thermostable human Sync2 · an experimental structure of the same protein · chain A against B, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8NA29
Elsewhere: UniProt Q8NA29 · AlphaFold DB Q8NA29

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