MolNFT v1 · #266051 · protein

AlphaFold monomer V2.0 prediction for nlr family card domain- containing protein 4 (Q3UP24)

Q3UP24 · Nlr family card domain-containing protein 4: “AlphaFold monomer V2.0 prediction for nlr family card domain- containing protein 4 (Q3UP24)”. 11 pockets (best druggability 0.81). MolNFT v1 #266051 on GenesisL1: 3D structure, binding…

Accession: Q3UP24
Type: protein
Length: 1,024 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x0EA189b2343A464f560b44103f6A3396Da1dA8a9
Molecule: Nlr family card domain-containing protein 4
UniProt: Q3UP24
Pockets: 11 · best druggability 0.81

Structure

1 distinct chain · 49% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nlr family card domain-containing protein 4	protein	1024	49% helix, 13% strand	Q3UP24

Pockets

11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1019	0.81	0.82	80	empty
2	761	0.77	0.81	66	empty
3	584	0.75	0.82	60	empty
4	293	0.53	0.75	24	empty
5	129	0.47	0.79	19	empty

Compared structures

4KXF · Crystal structure of NLRC4 reveals its autoinhibition mechanism · an experimental structure of the same protein · chain A against B, TM-score 0.77
4KXF · Crystal structure of NLRC4 reveals its autoinhibition mechanism · an experimental structure of the same protein · chain A against B, TM-score 0.77

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3UP24
Elsewhere: UniProt Q3UP24 · AlphaFold DB Q3UP24

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.