MolNFT v1 · #265971 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase nlk (D3ZSZ3)
D3ZSZ3: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase nlk (D3ZSZ3)”. 6 pockets (best druggability 0.74). MolNFT v1 #265971 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- D3ZSZ3
- Type
- protein
- Length
- 527 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xe9087b4D2Dbe42150dd056Cf60524296F5E4c09F
- Molecule
- SERINE/THREONINE-protein kinase nlk
- UniProt
- D3ZSZ3
- Pockets
- 6 · best druggability 0.74
Structure
1 distinct chain · 34% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase nlk | protein | 527 | 34% helix, 10% strand | D3ZSZ3 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 77 | 0.74 | 0.97 | 26 | empty |
| 2 | 705 | 0.73 | 0.79 | 77 | empty |
| 3 | 124 | 0.38 | 0.74 | 21 | empty |
| 4 | 65 | 0.35 | 0.78 | 17 | empty |
| 5 | 50 | 0.30 | 0.76 | 15 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D3ZSZ3
- Elsewhere: UniProt D3ZSZ3 · AlphaFold DB D3ZSZ3
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