MolNFT v1 · #265957 · protein
AlphaFold monomer V2.0 prediction for neuroligin-4, X-linked (Q8N0W4)
Q8N0W4: “AlphaFold monomer V2.0 prediction for neuroligin-4, X-linked (Q8N0W4)”. 10 pockets (best druggability 0.71). MolNFT v1 #265957 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8N0W4
- Type
- protein
- Length
- 816 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9f3206288ec82D2A7d94059Df552043DC8E2B729
- Molecule
- Neuroligin-4, X-linked
- UniProt
- Q8N0W4
- Pockets
- 10 · best druggability 0.71
Structure
1 distinct chain · 34% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuroligin-4, X-linked | protein | 816 | 34% helix, 10% strand | Q8N0W4 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 151 | 0.71 | 0.90 | 40 | empty |
| 2 | 631 | 0.70 | 0.78 | 57 | empty |
| 3 | 59 | 0.64 | 0.94 | 18 | empty |
| 4 | 325 | 0.58 | 0.76 | 26 | empty |
| 5 | 251 | 0.52 | 0.75 | 43 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 2WQZ · Crystal structure of synaptic protein neuroligin-4 in complex with neurexin-beta 1… · an experimental structure of the same protein · chain A against A, TM-score 0.66
- 2WQZ · Crystal structure of synaptic protein neuroligin-4 in complex with neurexin-beta 1… · an experimental structure of the same protein · chain A against A, TM-score 0.66
- 2XB6 · Revisited crystal structure of Neurexin1beta-Neuroligin4 complex · an experimental structure of the same protein · chain A against B, TM-score 0.66
- 2XB6 · Revisited crystal structure of NEUREXIN1BETA-NEUROLIGIN4 complex · an experimental structure of the same protein · chain A against B, TM-score 0.66
- 3BE8 · Crystal structure of the synaptic protein neuroligin 4 · an experimental structure of the same protein · chain A against A, TM-score 0.66
- 3BE8 · Crystal structure of the synaptic protein neuroligin 4 · an experimental structure of the same protein · chain A against A, TM-score 0.66
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8N0W4
- Elsewhere: UniProt Q8N0W4 · AlphaFold DB Q8N0W4
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