MolNFT v1 · #265948 · protein
AlphaFold monomer V2.0 prediction for neuroligin-1 (Q62765)
Q62765: “AlphaFold monomer V2.0 prediction for neuroligin-1 (Q62765)”. 7 pockets (best druggability 0.73). MolNFT v1 #265948 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q62765
- Type
- protein
- Length
- 843 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf2849A618395496fe4eEc310703B500e72ED79dD
- Molecule
- Neuroligin-1
- UniProt
- Q62765
- Pockets
- 7 · best druggability 0.73
Structure
1 distinct chain · 34% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuroligin-1 | protein | 843 | 34% helix, 9% strand | Q62765 |
Pockets
7 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 708 | 0.73 | 0.79 | 63 | empty |
| 2 | 516 | 0.70 | 0.80 | 49 | empty |
| 3 | 283 | 0.68 | 0.83 | 42 | empty |
| 4 | 75 | 0.63 | 0.91 | 19 | empty |
| 5 | 286 | 0.56 | 0.76 | 28 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 3BIX · Crystal structure of the extracellular esterase domain of neuroligin-1 · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 3BIX · Crystal structure of the extracellular esterase domain of Neuroligin-1 · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 3VKF · Crystal structure of neurexin 1BETA/NEUROLIGIN 1 complex · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 3VKF · Crystal Structure of Neurexin 1beta/Neuroligin 1 complex · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 3BIW · Crystal structure of the Neuroligin-1/Neurexin-1beta synaptic adhesion complex · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 3BIW · Crystal structure of the neuroligin-1/NEUREXIN-1BETA synaptic adhesion complex · an experimental structure of the same protein · chain A against A, TM-score 0.63
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q62765
- Elsewhere: UniProt Q62765 · AlphaFold DB Q62765
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