MolNFT v1 · #265880 · protein

AlphaFold monomer V2.0 prediction for homeobox protein nkx-2.1 (P23441)

P23441: “AlphaFold monomer V2.0 prediction for homeobox protein nkx-2.1 (P23441)”. 1 pocket (best druggability 0.29). MolNFT v1 #265880 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P23441
Type: protein
Length: 372 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9DA50d019C8E3c2eBF003087C8954415D6674d59
Molecule: Homeobox protein nkx-2.1
UniProt: P23441
Pockets: 1 · best druggability 0.29

Structure

1 distinct chain · 16% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Homeobox protein nkx-2.1	protein	372	16% helix, 0% strand	P23441

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	79	0.29	0.71	13	empty

Compared structures

1FTT · Thyroid transcription factor 1 homeodomain (rattus norvegicus) · an experimental structure of the same protein · chain A against A, TM-score 0.15
1FTT · Thyroid transcription factor 1 homeodomain (rattus norvegicus) · an experimental structure of the same protein · chain A against A, TM-score 0.15

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23441
Elsewhere: UniProt P23441 · AlphaFold DB P23441

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