MolNFT v1 · #265790 · protein

AlphaFold monomer V2.0 prediction for substance-K receptor (P21452)

P21452: “AlphaFold monomer V2.0 prediction for substance-K receptor (P21452)”. 2 pockets (best druggability 0.80). MolNFT v1 #265790 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P21452
Type: protein
Length: 398 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
Molecule: Substance-K receptor
UniProt: P21452
Pockets: 2 · best druggability 0.80

Structure

1 distinct chain · 67% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Substance-K receptor	protein	398	67% helix, 3% strand	P21452

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	919	0.80	0.82	67	empty
2	202	0.49	0.76	24	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

7XWO · Neurokinin A bound to active human neurokinin 2 receptor in complex with G324 · an experimental structure of the same protein · chain A against B, TM-score 0.64

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21452
Elsewhere: UniProt P21452 · AlphaFold DB P21452

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.