MolNFT v1 · #264238 · protein

AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa (A4SIW8)

A4SIW8: “AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa (A4SIW8)”. 7 pockets (best druggability 0.71). MolNFT v1 #264238 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A4SIW8
Type: protein
Length: 396 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
Molecule: NA(+)/H(+) antiporter nhaa
UniProt: A4SIW8
Pockets: 7 · best druggability 0.71

Structure

1 distinct chain · 73% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NA(+)/H(+) antiporter nhaa	protein	396	73% helix, 3% strand	A4SIW8

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	293	0.71	0.85	28	empty
2	195	0.56	0.80	28	empty
3	142	0.53	0.80	25	empty
4	78	0.45	0.80	14	empty
5	76	0.37	0.76	21	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4SIW8
Elsewhere: UniProt A4SIW8 · AlphaFold DB A4SIW8

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