MolNFT v1 · #264218 · protein

AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa 2 (A4X422)

A4X422: “AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa 2 (A4X422)”. 5 pockets (best druggability 0.69). MolNFT v1 #264218 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A4X422
Type: protein
Length: 453 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xb3c0C983Fc44934AC589D7131C08a72544EBB92E
Molecule: NA(+)/H(+) antiporter nhaa 2
UniProt: A4X422
Pockets: 5 · best druggability 0.69

Structure

1 distinct chain · 69% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NA(+)/H(+) antiporter nhaa 2	protein	453	69% helix, 1% strand	A4X422

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	351	0.69	0.82	48	empty
2	245	0.60	0.79	22	empty
3	166	0.50	0.77	20	empty
4	55	0.37	0.79	14	empty
5	86	0.34	0.74	23	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4X422
Elsewhere: UniProt A4X422 · AlphaFold DB A4X422

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