MolNFT v1 · #264216 · protein

AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa 2 (A4FCM4)

A4FCM4: “AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa 2 (A4FCM4)”. 6 pockets (best druggability 0.65). MolNFT v1 #264216 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A4FCM4
Type: protein
Length: 404 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
Molecule: NA(+)/H(+) antiporter nhaa 2
UniProt: A4FCM4
Pockets: 6 · best druggability 0.65

Structure

1 distinct chain · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NA(+)/H(+) antiporter nhaa 2	protein	404	77% helix, 0% strand	A4FCM4

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	400	0.65	0.79	47	empty
2	198	0.64	0.83	22	empty
3	67	0.41	0.81	22	empty
4	121	0.41	0.76	19	empty
5	95	0.38	0.74	15	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4FCM4
Elsewhere: UniProt A4FCM4 · AlphaFold DB A4FCM4

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