MolNFT v1 · #264172 · protein

AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa 1 (A4X6R9)

A4X6R9: “AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa 1 (A4X6R9)”. 7 pockets (best druggability 0.72). MolNFT v1 #264172 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A4X6R9
Type: protein
Length: 436 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x234294862B3cf379fDB96E48e9B87af08B673d87
Molecule: NA(+)/H(+) antiporter nhaa 1
UniProt: A4X6R9
Pockets: 7 · best druggability 0.72

Structure

1 distinct chain · 72% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NA(+)/H(+) antiporter nhaa 1	protein	436	72% helix, 1% strand	A4X6R9

Pockets

7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	77	0.72	0.96	22	empty
2	453	0.71	0.81	48	empty
3	284	0.60	0.78	26	empty
4	220	0.59	0.80	31	empty
5	260	0.51	0.75	40	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4X6R9
Elsewhere: UniProt A4X6R9 · AlphaFold DB A4X6R9

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