MolNFT v1 · #263419 · protein

AlphaFold monomer V2.0 prediction for nuclear factor of activated T-cells, cytoplasmic 4 (Q14934)

Q14934: “AlphaFold monomer V2.0 prediction for nuclear factor of activated T-cells, cytoplasmic 4 (Q14934)”. 2 pockets (best druggability 0.36). MolNFT v1 #263419 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q14934
Type: protein
Length: 902 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x460E4e7A7290a39D7Ba2ae71B7B7CEa0ecE29BeC
Molecule: Nuclear factor of activated T-cells, cytoplasmic 4
UniProt: Q14934
Pockets: 2 · best druggability 0.36

Structure

1 distinct chain · 6% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear factor of activated T-cells, cytoplasmic 4	protein	902	6% helix, 15% strand	Q14934

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	68	0.36	0.77	17	empty
2	92	0.34	0.74	18	empty

Compared structures

2YRP · Solution structure of the TIG domain from Human Nuclear factor of activated T-cells… · an experimental structure of the same protein · chain A against A, TM-score 0.12
2YRP · Solution structure of the tig domain from human nuclear factor of activated T-cells… · an experimental structure of the same protein · chain A against A, TM-score 0.12

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14934
Elsewhere: UniProt Q14934 · AlphaFold DB Q14934

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.