MolNFT v1 · #263329 · protein
AlphaFold monomer V2.0 prediction for sialidase-1 (O35657)
O35657: “AlphaFold monomer V2.0 prediction for sialidase-1 (O35657)”. 4 pockets (best druggability 0.73). MolNFT v1 #263329 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O35657
- Type
- protein
- Length
- 409 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xfA417B18af2a1c4a3E1bB0F48Eb0f4f629972ce1
- Molecule
- Sialidase-1
- UniProt
- O35657
- Pockets
- 4 · best druggability 0.73
Structure
1 distinct chain · 6% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sialidase-1 | protein | 409 | 6% helix, 43% strand | O35657 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 426 | 0.73 | 0.83 | 39 | empty |
| 2 | 163 | 0.58 | 0.82 | 25 | empty |
| 3 | 65 | 0.32 | 0.75 | 16 | empty |
| 4 | 54 | 0.31 | 0.77 | 18 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 8DU5 · Murine sialidase-1 (NEU1) · an experimental structure of the same protein · chain A against B, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O35657
- Elsewhere: UniProt O35657 · AlphaFold DB O35657
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