MolNFT v1 · #263311 · protein
AlphaFold monomer V2.0 prediction for neurolysin, mitochondrial (P42676)
P42676: “AlphaFold monomer V2.0 prediction for neurolysin, mitochondrial (P42676)”. 9 pockets (best druggability 0.81). MolNFT v1 #263311 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P42676
- Type
- protein
- Length
- 704 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6c2cC0486fb44B18D7Df3279EE7D533F42858Eba
- Molecule
- Neurolysin, mitochondrial
- UniProt
- P42676
- Pockets
- 9 · best druggability 0.81
Structure
1 distinct chain · 58% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neurolysin, mitochondrial | protein | 704 | 58% helix, 7% strand | P42676 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 717 | 0.81 | 0.84 | 72 | empty |
| 2 | 684 | 0.76 | 0.81 | 56 | empty |
| 3 | 222 | 0.56 | 0.79 | 24 | empty |
| 4 | 152 | 0.51 | 0.79 | 25 | empty |
| 5 | 78 | 0.48 | 0.83 | 15 | empty |
Compared structures
- 1I1I · Neurolysin (endopeptidase 24.16) crystal structure · an experimental structure of the same protein · chain A against P, TM-score 0.92
- 1I1I · Neurolysin (endopeptidase 24.16) crystal structure · an experimental structure of the same protein · chain A against P, TM-score 0.92
- 2O3E · Crystal structure of engineered neurolysin with thimet oligopeptidase specificity for… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2O3E · Crystal structure of engineered neurolysin with thimet oligopeptidase specificity for… · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 4FXY · Crystal structure of rat neurolysin with bound pyrazolidin inhibitor · an experimental structure of the same protein · chain A against P, TM-score 0.92
- 4FXY · Crystal structure of rat neurolysin with bound pyrazolidin inhibitor · an experimental structure of the same protein · chain A against P, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42676
- Elsewhere: UniProt P42676 · AlphaFold DB P42676
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