MolNFT v1 · #263112 · protein
AlphaFold monomer V2.0 prediction for neprilysin-2 (A0A0B4K692)
A0A0B4K692: “AlphaFold monomer V2.0 prediction for neprilysin-2 (A0A0B4K692)”. 11 pockets (best druggability 0.82). MolNFT v1 #263112 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A0A0B4K692
- Type
- protein
- Length
- 774 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
- Molecule
- Neprilysin-2
- Pockets
- 11 · best druggability 0.82
Structure
1 distinct chain · 55% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neprilysin-2 | protein | 774 | 55% helix, 6% strand | — |
Pockets
11 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 664 | 0.82 | 0.87 | 97 | empty |
| 2 | 154 | 0.64 | 0.86 | 28 | empty |
| 3 | 361 | 0.54 | 0.74 | 40 | empty |
| 4 | 138 | 0.50 | 0.79 | 25 | empty |
| 5 | 62 | 0.49 | 0.85 | 17 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
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