MolNFT v1 · #262982 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase NEK5 (Q7TSC3)
Q7TSC3: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase NEK5 (Q7TSC3)”. 5 pockets (best druggability 0.72). MolNFT v1 #262982 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q7TSC3
- Type
- protein
- Length
- 627 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x940bB0965EeFe24d3893a6Bf34f0F4F8890dF048
- Molecule
- SERINE/THREONINE-protein kinase NEK5
- UniProt
- Q7TSC3
- Pockets
- 5 · best druggability 0.72
Structure
1 distinct chain · 39% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase NEK5 | protein | 627 | 39% helix, 9% strand | Q7TSC3 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 675 | 0.72 | 0.79 | 61 | empty |
| 2 | 216 | 0.56 | 0.79 | 26 | empty |
| 3 | 159 | 0.48 | 0.77 | 28 | empty |
| 4 | 99 | 0.32 | 0.72 | 21 | empty |
| 5 | 51 | 0.27 | 0.74 | 11 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7TSC3
- Elsewhere: UniProt Q7TSC3 · AlphaFold DB Q7TSC3
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